Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Human (4760) Summary: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. Diseases associated with NEUROD1 include maturity-onset diabetes of the young, type 6, and insulin resistance. Using a probe to mouse neuroD, the human neuroD1 gene was isolated as well as six genomic clones with distinctly different restriction patterns. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. Free for academic non-profit institutions. Other users need a Commercial license, This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The BETA2 (neuroD) gene is expressed in endocrine cells during pancreas development and is essential for proper islet morphogenesis. It is a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors.The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. Best Sellers Customer Service Today's Deals New Releases Find a Gift Whole Foods Gift Cards Registry Sell AmazonBasics Coupons #FoundItOnAmazon Free Shipping Customer Service Today's Deals New Releases Find a Gift Whole Foods Gift Cards Registry Sell AmazonBasics Coupons #FoundItOnAmazon WikiGenes Search via NCBI Gene ID 4760. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. Neurogenic differentiation 1 (NeuroD1), also called β2, is a transcription factor of the NeuroD-type.It is encoded by the human gene NEUROD1.. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. Noma, T., Yoon, Y.S., Nakazawa, A. Background This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. It is involved in the differentiation of nervous system and development of pancreas. Protein tissue co-expression partners and The protein forms … Interacts with TCF3, TCF4 and TCF12. Maturity-onset diabetes of the young 6 (MODY6) [MIM:606394]: A form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease. al. This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. 2011), Virally transduced human fetal fibroblasts(Pang ZP et. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. (1999) [] Characterization of BrdU-positive neurons induced by transient global ischemia in adult hippocampus. ... INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases. Heterozygous point mutations in KLF11 (Kruppel-like factor 11, MODY7, … Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. CRISPR, shRNA, barcode), VectorBuilder BAC recombineering for NEUROD2, ProteoGenix Custom Cloning/Gene Synthesis Service (Subcloning and Mutagenesis/Gene Library Synthesis), Browse ESI BIO Cell Lines and PureStem Progenitors for NEUROD2, VectorBuilder Stable cell line generation for NEUROD2, Applied Biosystems by Thermo Fisher Scientific TaqMan® Assays for NEUROD2, epileptic encephalopathy, early infantile, 72, ATLAS of Genetics and Cytogenetics in Oncology and Haematology, Search disorders for NEUROD2 gene in PubMed and other databases, Search for latest publications for NEUROD2 gene in PubMed and other databases, View latest publications for NEUROD2 gene in Mastermind, R&D Systems NEUROD2 (NeuroD2) Primary Antibodies, R&D Systems custom NEUROD2 antibody, protein, and immunoassay development services, High-throughput Antibody Production Service, Epitope Tag Antibodies & Reporter Protein Antibodies, Search Knockout (KO) Validated Antibodies, Find your next knockout model in the Taconic Knockout Repository, Genetically Engineered Models Available Immediately, Pathogenic: EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 72, Epileptic encephalopathy, early infantile, 72 (EIEE72) [MIM:618374], Neurogenic Basic-Helix-Loop-Helix Protein. This gene is overexpressed in Fetal Brain (69.0). This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. lentivirus, AAV, adenovirus, MMLV, MSCV, baculovirus), VectorBuilder Custom and pre-made pooled libraries (ie. Hello Select your address Best Sellers Customer Service New Releases Whole Foods Find a Gift Registry Gift Cards AmazonBasics Sell #FoundItOnAmazon Free … Copyright © 1996-2020 , Weizmann Institute of Science. Interacts with ATOH8 (By similarity). The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. {ECO:0000269 PubMed:30323019}. al. GeneCards Summary for HDAC3 Gene: HDAC3 (histone deacetylase 3) is a protein-coding gene. Genomics 1996 Jun;34(3)418 … * NEUROD2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector -, * Gene synthesis, site-directed mutagenesis, subcloning, and more services -, * NEUROD2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector -, A. gosspyii yeast (Eremothecium gossypii), Actinobacteria (Mycobacterium tuberculosis), African malaria mosquito (Anopheles gambiae), Alpha proteobacteria (Wolbachia pipientis), Beta proteobacteria (Neisseria meningitidis), Firmicute Bacteria (Streptococcus pneumoniae), Fission Yeast (Schizosaccharomyces pombe), Schistosome Parasite (Schistosoma mansoni), Sea Urchin (Strongylocentrotus purpuratus), early infantile epileptic encephalopathy with burst-suppression. (1996) described the cloning and characterization of 2 additional NEUROD genes, NEUROD2 and NEUROD3. Non-annotated gene. NeuroD, also called Beta2, is a basic helix loop helix transcription factor expressed in certain parts of brain, beta pancreatic cells and enteroendocrine cells. This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. NEUROD2 (Neuronal Differentiation 2) is a Protein Coding gene. The orientations of theneuroD (noncoding regions in white; entire coding region in black), lacZ (in blue), and neo R gene (red) are indicated by arrows above below the genes. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. (and/or Entrez Gene and/or Ensembl if different), Santa Cruz Biotechnology (SCBT) Antibodies for NEUROD1, Santa Cruz Biotechnology (SCBT) CRISPR for NEUROD1. RefSeq Summary (NM_002500): This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. Showing 25 of 157 Results for NeuroD Search Time: 2 ms Showing 25 50 100 200 500 See All of 157 Results for NeuroD Search Time: 2 ms Export Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. Search aliases for NEUROD2 gene in PubMed and other databases, Epileptic Encephalopathy, Early Infantile, 72, Request up-to-date GeneHancer data (full dataset), See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB, Anti-NEUROD2 monoclonal antibody, clone FQS6246, Hi-Affi™ Recombinant Rabbit Anti-NEUROD2 Monoclonal Antibody (DS2425AB), Mouse Anti-NEUROD2 Recombinant Antibody (3E7), Show 14 available NEUROD2 Antibodies ranked by validation data, ProteoGenix Custom Antibody Production Services (Monoclonal/ Polyclonal/ Phage display/Ascites & CS), ProteoGenix Custom Monoclonal Antibody Humanization Services (Drug discovery services, Stable cell line, ADCC), Origene Custom Protein Services for NEUROD2, Browse Sino Biological Recombinant Proteins, Show 6 available NEUROD2 Proteins ranked by validation data, ProteoGenix Custom Recombinant Protein Production Services (E.coli/ Mammalian Cells/High throughput Screening), ProteoGenix Custom Peptide Synthesis Service / Conjugation and Modification service, Search results for available NEUROD2 related products ranked by validation data, Generate A Custom CRISPR Mouse Model For Your Study, CRISPR Clones for NEUROD2 - Select products 50% OFF >, VectorBuilder CRISPR vectors for NEUROD2 (ie. 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neurod gene cards

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